Computed tomography-based bronchial tree three-dimensional reconstruction and airway resistance evaluation in adolescent idiopathic scoliosis

• Published in: European spine journal Vol. 29; no. 8; pp. 1981 - 1992
• Main Authors: Wang, Juehan, Zhou, Bangjian, Yang, Xi, Zhou, Chunguang, Ling, Tingxian, Hu, Bowen, Song, Yueming, Liu, Limin
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.08.2020; Springer Nature B.V
• Subjects: Bronchus; Computed tomography; Medicine; Medicine & Public Health; Neurosurgery; Original Article; Radiography; Respiratory function; Respiratory tract; Rib; Scoliosis; Statistical analysis; Surgical Orthopedics; Thorax; Trachea; Vertebrae; Airway resistance; Adolescent idiopathic scoliosis (AIS); Spinal–thoracic deformity; Bronchial development; Computed tomographic three-dimensional reconstruction
• ISSN: 0940-6719; 1432-0932; 1432-0932
• DOI: 10.1007/s00586-020-06383-x

Purpose To investigate airway development and airway resistance by computed tomographic three-dimensional (3D) reconstruction of the bronchial tree in patients with adolescent idiopathic scoliosis (AIS). We evaluated factors predicting postoperative respiratory complications to provide timely treatment, prevent complications, and improve operative and anesthetic safety. Methods From August 2015 to August 2017, 53 AIS patients with a mean age of 15.4 years (range 10–20 years) were included in this study. Scoliotic parameters on radiographs were analyzed. Airway resistance was obtained by pulmonary function testing. All patients’ pulmonary bronchial trees were 3D-reconstructed via chest thin layer computed tomography to explore the correlation between the spinal–thoracic deformity parameters and airway resistance. Results Correlations between scoliotic parameters and airway development parameters were not statistically significant ( P  > 0.05). The scoliotic parameters such as Cobb angle, apical vertebral translation, rotation angle to sagittal plane, rotation angle to middle line, and apical vertebral body–rib ratio (AVB-R) were positively correlated with tracheal bifurcation angle ( R 2 : 0.429, 0.374, 0.430, 0.504, and 0.414, respectively; P  < 0.05). Cobb angle, rib hump, and apical vertebral body–rib ratio (AVB-R) were positively correlated with left principal bronchus length to right principal bronchus length (PBL-R) ( R 2 : 0.373, 0.503, and 0.377, respectively; P  < 0.05). Superficial area of bronchial tree (SABT) and narrow cross section of trachea (NCT) were negatively correlated with plethysmography Pre–Ref resistance ratio (Pre/Ref) ( R 2 : − 0.365 and − 0.452, respectively; P  < 0.05). SABT and NCT were negatively correlated with respiratory impedance (Zrs) ( R 2 : − 0.327 and − 0.436, respectively; P  < 0.05). Conclusions Pulmonary bronchial development in patients with AIS is affected by spinal–thoracic deformity. Comprehensive assessment of preoperative pulmonary function, especially airway resistance, is necessary in patients with AIS whether the thoracic scoliosis is severe or mild-to-moderate. Graphic abstract These slides can be retrieved under Electronic Supplementary Material.