Green and Low-temperature Synthesis of Carbon Dots for Simple Detection of Kaempferol

• Published in: Journal of fluorescence Vol. 33; no. 5; pp. 1971 - 1979
• Main Authors: Zeng, Hongyan, Peng, Huan, He, Hongmei, Feng, Jinrong, Sun, Yiqiang, He, Huanyu, Li, Li
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.09.2023; Springer Nature B.V
• Subjects: Analytical Chemistry; Anticancer properties; Ascorbic acid; Biochemistry; Biological and Medical Physics; Biomedical and Life Sciences; Biomedicine; Biophysics; Biotechnology; Carbon; Carbon dots; Flavonols; Fluorescence; Low temperature; Luminescence; Natural & organic foods; Oxidation; Photoluminescence; Sensors; Fluorescence; Simple detection; Carbon dots; Kaempferol; Low-temperature
• ISSN: 1053-0509; 1573-4994
• DOI: 10.1007/s10895-023-03204-4

As a common flavonols, kaempferol (Kae) has a broad market as health food and medicine for its anti-inflammatory, anti-oxidation, and anti-cancer properties. In this study, a novel convenient and simple fluorescent sensor based on carbon dots (CDs) for the detection of Kae was developed. The fluorescent CDs, with excellent photo-luminescence (PL) and up-conversion luminescence (UCPL) properties, were successfully prepared by low-temperature oil bath reaction based on ascorbic acid as carbon source at 90 °C in one pot. Under the optimal conditions, the fluorescence (FL) intensity of CDs was gradually quenched by the increasing addition of Kae with a linear relationship between F 0 /F and Kae concentration in a wide range from 5 µM to 100 µM with a detection limit of 0.38 µM. And this designed sensor was favourably applied for the detection of Kae in actual sample (xin-da-kang tablets). Moreover, the proposed CDs has great application prospects as a drug-sensor for detecting Kae due to its simple operation, economical and green materials, low equipment requirement, and rapid detection.