Genetic diversity and phylogenetic analysis of 29 Y-STR loci in the Tibetan population from Sichuan Province, Southwest China

Y-Chromosomal short tandem repeat polymorphisms (Y-STRs) are widely applied in human forensic cases and population genetic studies. There is a lack of information about the Sichuan Tibetan population in the Y-STR Haplotype Reference Database (YHRD, https://yhrd.org , release 59). In this study, 502...

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Published inInternational journal of legal medicine Vol. 134; no. 2; pp. 513 - 516
Main Authors Song, Feng, Xie, Mingkun, Xie, Bowen, Wang, Shuangshuang, Liao, Miao, Luo, Haibo
Format Journal Article
LanguageEnglish
Published Berlin/Heidelberg Springer Berlin Heidelberg 01.03.2020
Springer Nature B.V
Subjects
Dimensional analysis
Forensic Medicine
Haplotypes
Loci
Medical Law
Medicine
Medicine & Public Health
Phylogenetics
Population
Population Data
Population genetics
Populations
Y chromosomes
China
Haplotypes
Tibetan population
Population genetic analysis
Y-STR
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Summary:Y-Chromosomal short tandem repeat polymorphisms (Y-STRs) are widely applied in human forensic cases and population genetic studies. There is a lack of information about the Sichuan Tibetan population in the Y-STR Haplotype Reference Database (YHRD, https://yhrd.org , release 59). In this study, 502 unrelated male individuals residing in the Sichuan Province were recruited and genotyped at 29 Y-STR loci. A total of 479 haplotypes were observed, 460 (96.03%) of which were unique. The haplotype diversity (HD) and discrimination capacity (DC) for the Sichuan Tibetan population were 0.9998 and 0.9542, respectively. To reveal the genetic diversities and relationships between the Chinese Sichuan Tibetan and 29 other previously reported populations, forensic parameter analysis, multi-dimensional scaling, and phylogenetic reconstruction were performed. The results showed that the Sichuan Tibetan population was relatively isolated from other populations, suggesting that genetic proximity is in line with geographical boundaries.
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ISSN:0937-9827
1437-1596
DOI:10.1007/s00414-019-02043-y