Smoking, unemployment, female sex, obesity, and medication use yield worse outcomes in patellofemoral arthroplasty

• Published in: Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA Vol. 28; no. 9; pp. 2962 - 2969
• Main Authors: Desai, Vishal S., Pareek, Ayoosh, DeDeugd, Casey M., Sabbag, Orlando D., Krych, Aaron J., Cummings, Nancy M., Dahm, Diane L.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.09.2020; Springer Nature B.V
• Subjects: Analgesics, Opioid - therapeutic use; Antidepressants; Antidepressive Agents - therapeutic use; Arthroplasty; Arthroplasty, Replacement, Knee; Biomedical materials; Demographic variables; Demographics; Depressants; Employment; Female; Females; Follow-Up Studies; Humans; Joint surgery; Knee; Male; Median (statistics); Medicine; Medicine & Public Health; Middle Aged; Narcotics; Obesity; Obesity - complications; Opioids; Orthopedics; Patellofemoral Joint - surgery; Patient Reported Outcome Measures; Patients; Registries; Retrospective Studies; Risk analysis; Risk factors; Sex; Sex Factors; Smoking; Smoking - adverse effects; Statistical analysis; Surgical implants; Unemployment; Patellofemoral arthroplasty; Psychosocial; Employment; Opioids; Smoking; Anti-depressant
• ISSN: 0942-2056; 1433-7347
• DOI: 10.1007/s00167-019-05704-y

Purpose The purpose of this study was to identify effects of psychosocial and demographic factors on patellofemoral arthroplasty (PFA) outcomes. Methods Patients who underwent PFA by a single surgeon between 2002 and 2013 (min. 2 year follow-up) were included. Knee Society scores (KSS), UCLA, and Tegner Scores were prospectively collected in a designated arthroplasty registry. Patient records were retrospectively reviewed and univariate and multivariate statistical analyses were performed to assess the effect of psychosocial factors and demographic variables including patient sex, BMI, smoking and medication use, psychiatric history, and employment status on improvement between pre- and post-operative scores. Results Seventy-four knees in 55 patients (88% female) with a mean age of 51.8 (SD 8.8) and mean follow-up of 46.5 (SD 26.9) months were included. Patients showed significant improvement in all functional outcomes ( p  < 0.001). Mean improvement in KSS-F scores and median improvement in Tegner scores was greater in males compared to females (37.8 vs 16.1, p  = 0.007; 3.0 vs 2.0, p  = 0.07, respectively). Smokers showed less improvement in KSS-P compared to non-smokers (17.2 vs 30.0, p  = 0.028). Retired or employed patients had a greater mean improvement in KSS-F and median improvement in Tegner Scores compared to those were unemployed or on work disability ( p  = 0.022, p  = 0.01). Patients who reported using opioids and/or anti-depressants pre-operatively showed less improvement in UCLA scores ( p  = 0.006). Obese patients showed less improvement in both KSS-F and Tegner score compared to non-obese patients ( p  = 0.009, p  = 0.004). Conclusion Psychosocial factors influence the degree of improvement following PFA. Although patients showed overall improvement compared to their baseline scores, obese patients, smokers, unemployed/work disabled, and pre-operative use of opioids and/or anti-depressants were risk factors for decreased improvement… The consideration of psychosocial variables are clinically important when assessing a patient’s candidacy for PFA and improve pre-operative patient selection and counselling. Level of evidence Level IV.