Progress in self-healing hydrogels assembled by host-guest interactions: preparation and biomedical applications
Self-healing is one of the most fundamental properties of living tissues that allows them to withstand repeated damage. Self-healing hydrogels, which can spontaneously recover themselves after being ruptured, result in enhanced lifetimes for materials and open up a fascinating direction in materials...
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| Published in | Journal of materials chemistry. B, Materials for biology and medicine Vol. 7; no. 1; pp. 1637 - 1651 |
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| Main Authors | , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
England
14.03.2019
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| Online Access | Get full text |
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| Summary: | Self-healing is one of the most fundamental properties of living tissues that allows them to withstand repeated damage. Self-healing hydrogels, which can spontaneously recover themselves after being ruptured, result in enhanced lifetimes for materials and open up a fascinating direction in materials science. Host-guest interactions have been widely used in the construction of self-healing hydrogels. We have emphasized the preparation and biomedical applications of self-healing hydrogels assembled by host-guest interactions, focusing on hosts of cyclodextrins and cucurbit[
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]urils with various guests and tailored structures. The applications of self-healing hydrogels in biomedical fields such as drug delivery, encapsulation of cells and tissue engineering and 3D printing as well as interfacial adhesion were also summarized. At the end of this review, we propose the current challenges and future perspectives in this developing area.
Preparation and biomedical applications of self-healing hydrogels assembled from hosts of cyclodextrins and cucurbit[
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]urils with various guests were reviewed. |
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| Bibliography: | Prof. Li Ren earned his bachelor's degree and master's degree from South China University of Technology in 1994 and 1997, respectively, and PhD from Nanyang Technological University in 2005. He is currently the vice dean of the National Engineering Research Center for Tissue Restoration and Reconstruction at South China University of Technology. His main research interests focus on biomaterials and functional polymers. Dr Yong-Guang Jia is currently an associate professor of School of Materials Science and Engineering at South China University of Technology. He received his PhD in organic chemistry under the supervision of Prof. Jing Li from Nankai University, China in 2012, and finished his postdoc training with Prof. Julian Zhu at Université de Montréal, Canada. His main research interests, in the inter-disciplinary field of biomaterials, are in the design of supramolecular and stimuli-responsive polymers and hydrogels. Lili Cai received her master's degree in analytical chemistry from Nankai University, China in 2010. After she worked at Shandong Xinhua Pharmaceutical Company for two years, she is currently a research specialist at School of Materials Science and Engineering at South China University of Technology. Her research interests are in investigating preparations and applications of collagen-based materials. Jiahong Jin was born in 1994 in Hunan, China. He obtained his bachelor's degree from Shanghai University in 2016. Now he is pursuing his master's degree under the supervision of Prof. Liu and Prof. Jia at South China University of Technology. His research interests mainly focus on host-guest supramolecular materials. Yunhua Chen is an associate professor of Biomedical Engineering at South China University of Technology (SCUT). His research focuses on developing novel supramolecular biomaterials such as hydrogels, adhesives and macroporous scaffolds to promote tissue regeneration. Before joining SCUT as faculty in 2015, Yunhua received his PhD in polymer chemistry under the supervision of Prof. Stefan Bon from the University of Warwick, UK and completed a postdoc research fellowship at Warwick. Dr Sa Liu earned her bachelor's degree from Hebei University in 1990, master's degree from Guangzhou Institute of Chemistry, the Chinese Academy of Sciences in 1997 and PhD from South China University of Technology in 2000. She is now an associate professor at South China University of Technology. Her main research interests focus on biomedical materials. ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| ISSN: | 2050-750X 2050-7518 |
| DOI: | 10.1039/c8tb02547a |