Photoactivatable fluorescent proteins

The fluorescence characteristics of photoactivatable proteins can be controlled by irradiating them with light of a specific wavelength, intensity and duration. This provides unique possibilities for the optical labelling and tracking of living cells, organelles and intracellular molecules in a spat...

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Bibliographic Details
Published inNature reviews. Molecular cell biology Vol. 6; no. 11; pp. 885 - 890
Main Authors Lukyanov, Konstantin A, Verkhusha, Vladislav V, Chudakov, Dmitry M, Lukyanov, Sergey
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group 01.11.2005
Subjects
Fluorescence
Light
Localization
Proteins
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Summary:The fluorescence characteristics of photoactivatable proteins can be controlled by irradiating them with light of a specific wavelength, intensity and duration. This provides unique possibilities for the optical labelling and tracking of living cells, organelles and intracellular molecules in a spatio-temporal manner. Here, we discuss the properties of the available photoactivatable fluorescent proteins and their potential applications.
ISSN:1471-0072
1471-0080
DOI:10.1038/nrm1741