Intraarticular morphine administration provides pain relief after knee arthroscopy

• Published in: European journal of anaesthesiology Vol. 14; no. 2; p. 153
• Main Authors: Kanbak, M, Akpolat, N, Ocal, T, Doral, M N, Ercan, M, Erdem, K
• Format: Journal Article
• Language: English
• Published: England 01.03.1997
• Subjects: Adult; Analgesics, Opioid - administration & dosage; Analgesics, Opioid - therapeutic use; Arthroscopy; Double-Blind Method; Female; Humans; Injections, Intra-Articular; Knee - surgery; Male; Morphine - administration & dosage; Morphine - therapeutic use; Pain Measurement; Pain, Postoperative - drug therapy; Prospective Studies
• ISSN: 0265-0215
• DOI: 10.1046/j.1365-2346.1997.00081.x

This present study investigated the effects of intraarticular morphine administration in 1 mg and 5 mg doses on post-operative pain relief and analgesic requirements for patients undergoing arthroscopic procedures. At the end of the operation patients were randomly allocated in a double-blinded fashion into three groups. The control group (Group 1) received normal saline 20 mL intraarticularly. The patients in the second and third groups received intraarticular morphine sulphate 1 and 5 mg in saline 20 mL, respectively. Post-operative pain was assessed on the 1st, 6th and 24th hour by visual analogue scale (VSA). Supplementary analgesic requirement and possible complications were also followed. The intensity of pain and analgesic requirement were reduced more in the morphine 5 mg group than in the control group. It is concluded, that the administration of intraarticular morphine 5 mg provides long-lasting and effective analgesia after knee arthroscopy.