Hemodynamic studies in sickle cell anemia

Hemodynamic studies in 13 unselected patients with sickle cell anemia are reported. Twelve of these patients were also studied during mild exercise. The cardiac output at rest was elevated in all and rose significantly with exercise in 9 of the 12 patients. The importance of the increased percentage...

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Bibliographic Details
Published inCirculation (New York, N.Y.) Vol. 10; no. 5; pp. 653 - 662
Main Authors LEIGHT, L, SNIDER, T H, CLIFFORD, G O, HELLEMS, H K
Format Journal Article
LanguageEnglish
Published United States 01.11.1954
Subjects
Anemia
Anemia, Sickle Cell - physiology
Hemodynamics
Humans
Old Medline
ANEMIA, SICKLE CELL/physiology
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Summary:Hemodynamic studies in 13 unselected patients with sickle cell anemia are reported. Twelve of these patients were also studied during mild exercise. The cardiac output at rest was elevated in all and rose significantly with exercise in 9 of the 12 patients. The importance of the increased percentage extraction of oxygen by the tissues in modifying the response of the cardiac output is discussed. The similarity of the response to exercise in the majority of these chronically anemic patients compared with the normal response is described. Included in this series is one case with secondary cor pulmonale and one case of concurrent rheumatic heart disease.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:0009-7322
1524-4539
DOI:10.1161/01.CIR.10.5.653