A Study of Glycemic Response to Corinthian Raisins in Healthy Subjects and in Type 2 Diabetes Mellitus Patients

• Published in: Plant foods for human nutrition (Dordrecht) Vol. 68; no. 2; pp. 145 - 148
• Main Authors: Kanellos, Panagiotis T., Kaliora, Andriana C., Liaskos, Christos, Tentolouris, Nikolaos K., Perrea, Despina, Karathanos, Vaios T.
• Format: Journal Article
• Language: English
• Published: Boston Springer US 01.06.2013; Springer
• Subjects: Adult; Aged; Biological and medical sciences; Blood Glucose - analysis; Blood Glucose - metabolism; Chemistry; Chemistry and Materials Science; Chemistry/Food Science; Diabetes Mellitus, Type 2 - blood; Diabetes Mellitus, Type 2 - diet therapy; Diabetes Mellitus, Type 2 - drug therapy; Diabetes Mellitus, Type 2 - metabolism; Diabetes. Impaired glucose tolerance; Ecology; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; Etiopathogenesis. Screening. Investigations. Target tissue resistance; Feeding. Feeding behavior; Female; Food Science; Fundamental and applied biological sciences. Psychology; Glycemic Index; Humans; Insulin - blood; Male; Medical sciences; Middle Aged; Nutrition; Original Paper; Plant Physiology; Vertebrates: anatomy and physiology, studies on body, several organs or systems; Vitis; Young Adult; Blood glucose; Corinthian raisins; Insulinemic response; Glycemic response; Endocrinopathy; Type 2 diabetes; Human; Biological fluid; Healthy subject; Nutrition; Metabolic diseases; Glucose; Blood; Carbohydrate
• ISSN: 0921-9668; 1573-9104
• DOI: 10.1007/s11130-013-0348-y

This study was designed to evaluate the metabolic response to Corinthian raisins in healthy and in patients with type 2 diabetes mellitus. Healthy subjects ( n  = 15) and diabetic patients ( n  = 15) received 74 g raisins or 50 g glucose as reference food. Blood samples were collected at time 0 (before the consumption) and 30, 60, 90, 120, 150 and 180 min after raisin or glucose consumption. There was no significant difference in baseline glucose and insulin between raisins and reference in both groups. The difference at glucose peaks between raisins and reference was significant in healthy and in diabetics. Glycemic and insulinemic responses were decreased after raisin consumption compared to reference. An estimate of the glycemic index would be 66.3 ± 3.4.