A matheuristic for the selection of beam directions and dose distribution in Radiotherapy Planning

In this paper a matheuristic using a combined Genetic Algorithm (GA) and exact method approach is proposed for selecting the position of the beams and dose distribution in Intensity Modulated Radiotherapy Planning (IMRT). GA selects a set of beams, for which the dose distribution is determined in th...

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Bibliographic Details
Published inJournal of physics. Conference series Vol. 616; no. 1; pp. 12012 - 12021
Main Authors Obal, T M, Florentino, H O, Gevert, V G, Jones, D F, Ouelhadj, D, Volpi, N M P, Wilhelm, V E
Format Journal Article
LanguageEnglish
Published Bristol IOP Publishing 22.05.2015
Subjects
Genetic algorithms
Optimization
Performance evaluation
Physics
Radiation therapy
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Summary:In this paper a matheuristic using a combined Genetic Algorithm (GA) and exact method approach is proposed for selecting the position of the beams and dose distribution in Intensity Modulated Radiotherapy Planning (IMRT). GA selects a set of beams, for which the dose distribution is determined in the process of the GA's evaluation, using an optimisation model that is solved by an Interior Point method. Two instances are used to evaluate the performance of the matheuristic, comparing to the optimum solution, in terms of solution and computation time, found using the exact methodology of Branch and Bound. The results show that the matheuristic is appropriate to this problem in the case study proposed, as it is extremely faster than the exact method and also have reached the optimum solution in several experiments done.
ISSN:1742-6588
1742-6596
DOI:10.1088/1742-6596/616/1/012012