Antimicrobial activity of Alepidea amatymbica

Alepidea amatymbica Eckl. & Zeyh (Apiaceae) is a medicinal plant traditionally used for the treatment of various diseases including asthma, influenza, and diarrhea in South Africa. The antimicrobial activities of the acetone and methanol extracts of the leaf, stem, rhizome, and root of the speci...

Full description

Saved in:
Bibliographic Details
Published inPharmaceutical biology Vol. 47; no. 5; pp. 436 - 439
Main Authors Afolayan, A.J, Lewu, F.B
Format Journal Article
LanguageEnglish
Published Informa UK Ltd 01.05.2009
Taylor & Francis
Subjects
acetone
Alepidea amatymbica
antimicrobial
antimicrobial properties
Apiaceae
Aspergillus flavus
Aspergillus niger
asthma
diarrhea
diarrhoea
ethnobotany
Gram-positive bacteria
leaves
medicinal plants
methanol
microbial growth
Penicillium notatum
plant extracts
rhizomes
roots
stems
traditional medicine
South Africa
Online AccessGet full text

Cover

More Information
Summary:Alepidea amatymbica Eckl. & Zeyh (Apiaceae) is a medicinal plant traditionally used for the treatment of various diseases including asthma, influenza, and diarrhea in South Africa. The antimicrobial activities of the acetone and methanol extracts of the leaf, stem, rhizome, and root of the species were assessed in an effort to validate the traditional medicinal uses of this herb, especially for the treatment of infectious diseases. Ten bacterial and three fungal species were bioassayed using the agar dilution method. All the extracts demonstrated appreciable activities against three Gram-positive bacteria. These bacteria have been implicated in different respiratory diseases. The inhibitory activity of some of the extracts against pathogens implicated in diarrhea diseases further validated the use of the herb in traditional medicine. Except for acetone leaf extract against Aspergillus flavus and Aspergillus niger, all the extracts showed more than 50% mycotic inhibition with activity ranging from 51.39% on A. niger to 81.11% on Penicillium notatum at  5 mg mL−1 which was the highest concentration tested in the study. The ability of the herb to inhibit the growth of various bacteria and fungi species is an indication of the broad-spectrum antimicrobial potential of A. amatymbica; this further validates the use of the herb for various diseases by the people of the Eastern Cape.
ISSN:1388-0209
1744-5116
DOI:10.1080/13880200902817919