The Characterization of Rabies Soluble Antigens

The C.S.I.R. and U.C.T. Virus Research Unit, Department of Pathology, University of Cape Town, South Africa ABSTRACT SUMMARY: Virus-free extracts of rabies-infected suckling mouse brains contain a relatively large antigen which is slowly sedimentable at 70,000 g and resistant to trypsin; a smaller a...

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Bibliographic Details
Published inJournal of general microbiology Vol. 27; no. 3; pp. 415 - 426
Main Author Mead, T. H
Format Journal Article
LanguageEnglish
Published England Soc General Microbiol 01.03.1962
Subjects
Antigens
Humans
Old Medline
Rabies - immunology
Rabies Vaccines
RABIES/immunology
ANTIGENS
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Summary:The C.S.I.R. and U.C.T. Virus Research Unit, Department of Pathology, University of Cape Town, South Africa ABSTRACT SUMMARY: Virus-free extracts of rabies-infected suckling mouse brains contain a relatively large antigen which is slowly sedimentable at 70,000 g and resistant to trypsin; a smaller antigen which is destroyed by trypsin; probably at least two antigens of intermediate size also probably sensitive to trypsin. The antigens differ but slightly from each other and from one or more brain components in electrophoretic mobility in agar and in chromatographic behaviour on DEAE cellulose.
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ISSN:0022-1287
DOI:10.1099/00221287-27-3-415