Proteome Analysis of Inhibitory Effect of Gadolinium on Sinorhizobium fredii

• Published in: Journal of rare earths Vol. 25; no. 1; pp. 106 - 110
• Main Authors: Weiwei, Han, Shihua, Shen, Peidong, Tai
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.02.2007; Key Laboratory of Photosynthesis and Environmental Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China; Graduate School of Chinese Academy of Sciences, Beijing 100039, China%Key Laboratory of Photosynthesis and Environmental Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China%Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang 110016, China
• Subjects: gadolinium; proteome; rare earth elements; Sinorhizobium fredii; Sinorhizobium fredii; rare earth elements; proteome; gadolinium
• ISSN: 1002-0721; 2509-4963
• DOI: 10.1016/S1002-0721(07)60054-4

The inhibitory effect of gadolinium on Sinorhizobium fredii USDA 205 was studied on a global scale using two-dimensional gel electrophoresis and MALDI-TOF MS. The results indicated that 22 proteins were significantly affected by 1 mmol·L −1 Gd 3+ treatment when compared with an untreated control. Among these proteins, nine were up-regulated and thirteen were down-regulated. The differently expressed proteins were classified into 8 functional categories based on their functions, including transporters, proteins for cellular defence, and proteins involved in metabolism.