Sensitivity of Gd-DTPA-enhanced MR imaging of benign extraaxial tumors

The effect of gadolinium diethylenetriaminepentaacetic acid (DTPA) on the sensitivity of cranial magnetic resonance (MR) imaging was measured in a prospective blinded study. Twenty-two consecutive patients with benign extraaxial tumors underwent MR imaging on a 1.5-T system without and with intraven...

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Published inRadiology Vol. 166; no. 3; p. 829
Main Authors Haughton, V M, Rimm, A A, Czervionke, L F, Breger, R K, Fisher, M E, Papke, R A, Hendrix, L E, Strother, C M, Turski, P A, Williams, A L
Format Journal Article
LanguageEnglish
Published United States 01.03.1988
Subjects
Adenoma - diagnosis
Brain Neoplasms - diagnosis
Gadolinium
Gadolinium DTPA
Humans
Magnetic Resonance Imaging
Meningioma - diagnosis
Neuroma, Acoustic - diagnosis
Organometallic Compounds
Pentetic Acid
Pituitary Neoplasms - diagnosis
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Summary:The effect of gadolinium diethylenetriaminepentaacetic acid (DTPA) on the sensitivity of cranial magnetic resonance (MR) imaging was measured in a prospective blinded study. Twenty-two consecutive patients with benign extraaxial tumors underwent MR imaging on a 1.5-T system without and with intravenous administration of Gd-DTPA. Readers independently interpreted the unenhanced and enhanced images without clinical information. The interpretations were compared with the anatomically verified diagnoses. Gd-DTPA improved the sensitivity of MR imaging for benign extraaxial tumors, especially in cases of residual or recurrent acoustic neuromas, multiple tumors (e.g., neurofibromatosis), or inconclusive unenhanced MR images. Enhancement with Gd-DTPA impaired the identification of a skull base tumor.
ISSN:0033-8419
DOI:10.1148/radiology.166.3.3340779