PULMONARY ARTERY STENOSIS ASSOCIATED WITH DUCTUS ARTERIOSUS FOLLOWING MATERNAL RUBELLA

Nine patients with pulmonary artery stenosis associated with patent ductus arteriosus following maternal rubella are described. Five of the patients had bilateral pulmonary artery stenosis and four cases involved only the right pulmonary artery. Mild pulmonary valvular stenosis was present in five a...

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Published inCirculation (New York, N.Y.) Vol. 29; no. 4; pp. SUPPL:514 - 522
Main Authors EMMANOUILIDES, G C, LINDE, L M, CRITTENDEN, I H
Format Journal Article
LanguageEnglish
Published United States 01.04.1964
Subjects
Angiocardiography
Cardiac Catheterization
Cataract
Constriction, Pathologic
Deafness
Ductus Arteriosus
Ductus Arteriosus, Patent
Female
Fetal Diseases
Heart Septal Defects
Heart Septal Defects, Ventricular
Humans
Hypertension
Hypertension, Pulmonary
Infant
Infant, Newborn
Infant, Premature, Diseases
Maternal-Fetal Exchange
Old Medline
Pregnancy
Pregnancy Complications, Infectious
Pulmonary Artery
Pulmonary Valve Stenosis
Rubella
PULMONARY ARTERY
FETAL DISEASES
MATERNAL-FETAL EXCHANGE
ANGIOCARDIOGRAPHY
HEART CATHETERIZATION
PULMONARY VALVE STENOSIS
PREGNANCY
HYPERTENSION, PULMONARY
INFANT, PREMATURE, DISEASES
DUCTUS ARTERIOSUS
DUCTUS ARTERIOSUS, PATENT
PREGNANCY COMPLICATIONS, INFECTIOUS
RUBELLA
HEART SEPTAL DEFECTS, VENTRICULAR
DEAFNESS
CATARACT
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Summary:Nine patients with pulmonary artery stenosis associated with patent ductus arteriosus following maternal rubella are described. Five of the patients had bilateral pulmonary artery stenosis and four cases involved only the right pulmonary artery. Mild pulmonary valvular stenosis was present in five and a ventricular septal defect in one. The persistence of a systolic murmur transmitted to the lateral chest wall, after ligation or division of a patent ductus arteriosus, should arouse suspicion of the presence of pulmonary artery stenosis. This report supports the recently described implication of maternal rubella as a cause of pulmonary artery stenosis. Careful auscultation in patients with history of maternal rubella may discover the presence of such an arterial anomaly, but cardiac catheterization and angiocardiography are necessary for substantiation of diagnosis. The natural history of these lesions is not known.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0009-7322
1524-4539
DOI:10.1161/01.CIR.29.4.514