Differences of cerebral oxygen saturation in dialysis patients: a comparison of three principals of near infrared spectroscopy

• Published in: Journal of anesthesia Vol. 37; no. 6; pp. 861 - 867
• Main Authors: Yagi, Yasunori, Kubo, Yasunori, Hoshino, Koji, Okada, Kazufumi, Hotta, Kiyohiko, Shinohara, Nobuo, Morimoto, Yuji
• Format: Journal Article
• Language: English
• Published: Singapore Springer Nature Singapore 01.12.2023
• Subjects: Anesthesiology; Brain; Critical Care Medicine; Emergency Medicine; Humans; Intensive; Medicine; Medicine & Public Health; Original Article; Oximetry - methods; Oxygen; Oxygen Saturation; Pain Medicine; Renal Dialysis; Spectroscopy, Near-Infrared - methods; Near infrared spectroscopy; Dialysis; Cerebral oxygenation
• ISSN: 0913-8668; 1438-8359
• DOI: 10.1007/s00540-023-03245-w

Purpose It has been reported that cerebral oxygen saturation (rSO 2 ) measured by near infrared spectroscopy is low in dialysis patients. We compared the rSO 2 values of dialysis patients before living donor kidney transplantation and their donors as controls by using three spectroscopes that utilize different principals, the INVOS 5100C (spatially resolved spectroscopy), FORE-SIGHT ELITE (modified Beer–Lambert law) and tNIRS-1 (time-resolved spectroscopy). Methods Before induction of anesthesia, the sensors of one of the three spectroscopes were placed on the forehead and rSO 2 values were recorded followed by the same measurement using the other two spectroscopes. The primary objective was to compare the rSO 2 values of the dialysis patients and controls using the three spectroscopes by the unpaired t test. Then we compared the rSO 2 values among the spectroscopes in both dialysis patients and controls by one-way ANOVA. Finally, we examined the relations between the rSO 2 values and the physiological values by using the Pearson correlation coefficient. Results Fifteen pairs of dialysis patients and controls were studied. With the INVOS 5100 C, the values of the dialysis patients (59.7 ± 9.7% (mean ± standard deviation) were 13% lower than those of the controls (73.3 ± 6.9%) ( P  < 0.01). With the tNIRS-1, the values were 57.8 ± 4.8% in the dialysis patients and 63.3 ± 3.5% in the controls ( P  < 0.01). Almost no differences were observed with the FORE-SIGHT ELITE (71.6 ± 4.9% [dialysis patients] vs. 70.8 ± 4.3% [Controls]) ( P  = 0.62). Among the spectroscopes, the values were significantly different in both dialysis patients and controls. For the INVOS 5100C and tNIRS-1, correlation coefficients between rSO 2 values and blood Hb and serum Alb were more than 0.5. Conclusions The rSO 2 values for comparisons between the dialysis patients and the controls were different according to differences of the principles of the near infrared spectroscopes. In the INVOS 5100C and tNIRS-1, rSO 2 values may be related to blood Hb and serum Alb.