Cerebral Microembolism During Coronary Angiography A Randomized Comparison Between Femoral and Radial Arterial Access

• Published in: Stroke (1970) Vol. 42; no. 5; pp. 1475 - 1477
• Main Authors: JURGA, Juliane, NYMAN, Jesper, TORNVALL, Per, NASTASE MANNILA, Maria, SVENARUD, Peter, VAN DER LINDEN, Jan, SARKAR, Nondita
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD Lippincott Williams & Wilkins 01.05.2011
• Subjects: Aged; Angina Pectoris - diagnostic imaging; Biological and medical sciences; Coronary Angiography - adverse effects; Female; Femoral Artery; Humans; Intracranial Embolism - epidemiology; Investigative techniques, diagnostic techniques (general aspects); Male; Medical sciences; Medicin och hälsovetenskap; Middle Aged; Nervous system; Neurology; Prevalence; Radial Artery; Radiodiagnosis. Nmr imagery. Nmr spectrometry; Retrospective Studies; Risk Factors; Vascular diseases and vascular malformations of the nervous system; Doppler ultrasound study; microemboli; Stroke; Nervous system diseases; Cardiovascular disease; Coronary arteriography; Cerebral disorder; Encephalon; Microembolism; Vascular disease; radial; transcranial Doppler; Central nervous system disease; Comparative study; Cerebrovascular disease; coronary angiography
• ISSN: 0039-2499; 1524-4628; 1524-4628
• DOI: 10.1161/STROKEAHA.110.608638

Microemboli observed during coronary angiography can cause silent ischemic cerebral lesions. The aim of this study was to investigate if the number of particulate cerebral microemboli during coronary angiography is influenced by access site used. Fifty-one patients with stable angina pectoris referred for coronary angiography were randomized to right radial or right femoral arterial access. The number of particulate microemboli passing the middle cerebral arteries was continuously registered with transcranial Doppler. The median (minimum-maximum range) numbers of particulate emboli were significantly higher with radial 10 (1-120) than with femoral 6 (1-19) access. More particulate microemboli passed the right middle cerebral artery with the radial access. This study indicates that the radial access used for coronary angiography generates more particulate cerebral microemboli than the femoral access and thus may influence the occurrence of silent cerebral injuries.