Metal coordination as a tool for controlling the self-assembling and gelation properties of novel type cholic amide–phenanthroline gelating agent
(3α,7α,12α)-Trihydroxy- N-[1,10-phenanthrolin-5-yl]-5β-cholan-24-amide was found to be a powerful gelating agent for methanol–water in gelator to solvent ratio starting from 0.1% in absence of metal ion. Formation of phenanthroline–zinc (II) 2:1 complex changes dramatically gelating properties; when...
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Published in | Tetrahedron Vol. 59; no. 23; pp. 4069 - 4076 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
OXFORD
Elsevier Ltd
02.06.2003
Elsevier |
Subjects | |
Online Access | Get full text |
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Summary: | (3α,7α,12α)-Trihydroxy-
N-[1,10-phenanthrolin-5-yl]-5β-cholan-24-amide was found to be a powerful gelating agent for methanol–water in gelator to solvent ratio starting from 0.1% in absence of metal ion. Formation of phenanthroline–zinc (II) 2:1 complex changes dramatically gelating properties; when stored, it dissolves into clear solution without Tyndall effect and this solution, when heated to ca. 70°C reversibly forms a gel again, without chemical change as proven by NMR spectrometry. Structures of the gels of cholic amide–phenanthroline and its Zn
2+ complex were studied by SEM.
Steroid–phenanthroline conjugate was found to be a powerful gelating agent for methanol–water. Formation of phenanthroline–zinc (II) 2:1 complex changes the gelating properties; when stored, it dissolves into solution and this solution, when heated reversibly forms a gel again. Complexes and gels were studied by spectroscopic methods and SEM. |
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ISSN: | 0040-4020 1464-5416 |
DOI: | 10.1016/S0040-4020(03)00587-8 |