Rearranged taxoids from Taxus yunnanensis

Two rearranged 2(3-20)abeotaxanes were isolated from the leaves and stems of Taxus yunnanensis, and designated as taxin B and 2-deacetyltaxin B. The structure of taxin B with a unique 6/10/6 skeleton was deduced on the basis of 1H-NMR, 13C-NMR, 1H-1H COSY, DEPT, NOE, and mass spectra and confirmed b...

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Bibliographic Details
Published inPlanta medica Vol. 61; no. 4; p. 375
Main Authors Yue, Q, Fang, Q.C, Liang, X.T, He, C.H, Jing, X.L. (Chinese Academy of Medical Sciences, Beijing (China). Peking Union Medical College. Inst. of Materia Medica)
Format Journal Article
LanguageEnglish
Published Germany 01.08.1995
Subjects
Alkaloids - chemistry
Alkaloids - isolation & purification
COMPOSICION QUIMICA
COMPOSITION CHIMIQUE
Crystallography, X-Ray
ESTRUCTURA QUIMICA
FEUILLE
HOJAS
Magnetic Resonance Spectroscopy
Models, Molecular
Molecular Conformation
Paclitaxel - analogs & derivatives
Plant Extracts
Plant Leaves
Plant Stems
PLANTAS MEDICINALES
PLANTE MEDICINALE
Plants, Medicinal
Spectrometry, Mass, Fast Atom Bombardment
STRUCTURE CHIMIQUE
Structure-Activity Relationship
TALLO
TAXUS
TIGE
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Summary:Two rearranged 2(3-20)abeotaxanes were isolated from the leaves and stems of Taxus yunnanensis, and designated as taxin B and 2-deacetyltaxin B. The structure of taxin B with a unique 6/10/6 skeleton was deduced on the basis of 1H-NMR, 13C-NMR, 1H-1H COSY, DEPT, NOE, and mass spectra and confirmed by X-ray crystallographic analysis. The structure of 2-deacetyltaxin B is elucidated by analog.
Bibliography:F60
97B6323
ISSN:0032-0943
1439-0221
DOI:10.1055/s-2006-958109