A new short synthesis of deoxyhydantocidin derivatives

Using erythronolactol 8 as chiral C 4 synthon, a new short synthetic pathway was developed to obtain two hydantoin 2′-deoxyribonucleoside epimer derivatives 15a and 15b. Using erythronolactol 8 as chiral C 4 synthon, a new short synthetic pathway was developed to obtain the two hydantoin 2′-deoxyrib...

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Bibliographic Details
Published inTetrahedron letters Vol. 39; no. 20; pp. 3129 - 3132
Main Authors Renard, Annabelle, Kotera, Mitsuharu, Lhomme, Jean
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier Ltd 14.05.1998
Elsevier
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
4-O-BENZYL-2,3-O-ISOPROPYLIDENE-L-THREOSE
ANOMERIC SPIRO NUCLEOSIDES
USEFUL BUILDING BLOCK
HERBICIDAL ACTIVITY
HYDANTOCIDIN
CYCLIZATION
OLIGONUCLEOTIDES
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Summary:Using erythronolactol 8 as chiral C 4 synthon, a new short synthetic pathway was developed to obtain two hydantoin 2′-deoxyribonucleoside epimer derivatives 15a and 15b. Using erythronolactol 8 as chiral C 4 synthon, a new short synthetic pathway was developed to obtain the two hydantoin 2′-deoxyribonucleoside epimer derivatives 15a and 15b.
ISSN:0040-4039
1873-3581
DOI:10.1016/S0040-4039(98)00438-9