Failure to Learn from Repeated Mistakes: Persistent Decision-Making Impairment as Measured by the Iowa Gambling Task in Patients with Ventromedial Prefrontal Cortex Lesions

Although frontal patients show impaired decision-making on the Iowa Gambling Task (IGT), there has been no follow-up study to date to determine whether there is recovery of function over time. We examined neurological participants’ performance on repeated administrations of the IGT over the course o...

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Bibliographic Details
Published inJournal of the International Neuropsychological Society Vol. 18; no. 5; pp. 927 - 930
Main Authors Waters-Wood, Samantha M., Xiao, Lin, Denburg, Natalie L., Hernandez, Michael, Bechara, Antoine
Format Journal Article
LanguageEnglish
Published New York, USA Cambridge University Press 01.09.2012
Subjects
Adult
Aged
Analysis of Variance
Brain Injuries - complications
Brain Injuries - pathology
Cognition Disorders - diagnosis
Cognition Disorders - etiology
Decision making
Decision Making - physiology
Education
Expected values
Female
Games, Experimental
Head injuries
Humans
Learning Disorders - diagnosis
Learning Disorders - etiology
Male
Middle Aged
Nervous system
Neuropsychological Tests
Patients
Prefrontal Cortex - pathology
Trauma
Variance analysis
United States > US
Iowa
Decision making
Neuropsychological tests
Prefrontal cortex
Diagnosis
Choice behavior
Clinical psychology
Reliability
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Summary:Although frontal patients show impaired decision-making on the Iowa Gambling Task (IGT), there has been no follow-up study to date to determine whether there is recovery of function over time. We examined neurological participants’ performance on repeated administrations of the IGT over the course of 6 years. We found that, while non-neurological participants showed considerable improvement due to practice effects on the IGT, patients with ventromedial prefrontal cortex (VMPFC) damage persisted in showing impaired performance on each retest. These results validate the clinical observations that VMPFC dysfunction does not appear to be subject to autonomous recovery over time in real-life. (JINS, 2012, 18, 1–4)
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ISSN:1355-6177
1469-7661
1469-7661
DOI:10.1017/S135561771200063X