Antiulcer action of Styrax camporum and Caesalpinia ferrea in rats

Stem extracts of Styrax camporum Pohl and Caesalpinia ferrea Martius were administered orally and intraperitoneally to rats and effected a decrease in the acute ulceration number. The volume, pH, and hydrochloric acid concentration of gastric secretions were measured after administration of both ext...

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Bibliographic Details
Published inPlanta medica Vol. 60; no. 2; p. 118
Main Authors Bacchi, E.M, Sertie, J.A.A. (Universidade de Sao Paulo (Brazil). Faculdade de Ciencias Farmaceuticas. Dept. de Farmacia)
Format Journal Article
LanguageEnglish
Published Germany 01.04.1994
Subjects
Animals
Anti-Ulcer Agents - pharmacology
Brazil
CAESALPINIA
COMPOSICION QUIMICA
COMPOSITION CHIMIQUE
FARMACOLOGIA
Female
GASTRITE
GASTRITIS
PHARMACOLOGIE
Plant Extracts - pharmacology
PLANTAS MEDICINALES
PLANTE MEDICINALE
Plants, Medicinal
Rats
Rats, Wistar
STYRACACEAE
TALLO
TIGE
Brazil
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Summary:Stem extracts of Styrax camporum Pohl and Caesalpinia ferrea Martius were administered orally and intraperitoneally to rats and effected a decrease in the acute ulceration number. The volume, pH, and hydrochloric acid concentration of gastric secretions were measured after administration of both extracts, atropine, and cimetidine. After oral administration there was a decrease in the gastric secretion volume without modification of the other gastric secretion parameters studied. There were modifications, however, when the extracts were administered intraperitoneally. Analgesy, influence on sleeping time, and spontaneous motor activity test results indicate a probable absence of central action components in the extracts.
Bibliography:F60
97B7180
ISSN:0032-0943
1439-0221
DOI:10.1055/s-2006-959430