Surgical Management of High-Grade Meningiomas

Maximal resection with the preservation of neurological function are the mainstays of the surgical management of high-grade meningiomas. Surgical morbidity is strongly associated with tumor size, location, and invasiveness, whereas patient survival is strongly associated with the extent of resection...

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Bibliographic Details
Published inCancers Vol. 16; no. 11; p. 1978
Main Authors Pacult, Mark A, Przybylowski, Colin J, Raza, Shaan M, DeMonte, Franco
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 23.05.2024
MDPI
Subjects
Blood vessels
Care and treatment
Cranial nerves
Diagnosis
Invasiveness
Meningioma
Morbidity
Pathology
Patient outcomes
Patients
Review
Surgical outcomes
Survival
Tomography
Tumors
United States
meningioma
Simpson grade
anaplastic
extent of resection
gross total resection
atypical
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Summary:Maximal resection with the preservation of neurological function are the mainstays of the surgical management of high-grade meningiomas. Surgical morbidity is strongly associated with tumor size, location, and invasiveness, whereas patient survival is strongly associated with the extent of resection, tumor biology, and patient health. A versatile microsurgical skill set combined with a cogent multimodality treatment plan is critical in order to achieve optimal patient outcomes. Continued refinement in surgical techniques in conjunction with directed radiotherapeutic and medical therapies will define future treatment.
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ISSN:2072-6694
2072-6694
DOI:10.3390/cancers16111978