Mannitol evaluated mineral absorption and bone retention in ovariectomized rats

Indigestible sugars are used in food production and pharmaceutical industry due to their desirable properties. The effects of mannitol on Ca and Mg absorption and retention in ovariectomized rats were evaluated. Five weeks old ovariectomized Wistar rats were given Ca, Mg-deficient diet for 28 days t...

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Published inCzech Journal of Food Sciences Vol. 37; no. 5; pp. 319 - 324
Main Authors Xiao, Jin, Sakaguchi, Ei, Shi, Bin Lin
Format Journal Article
LanguageEnglish
Czech
Slovak
Published Prague Czech Academy of Agricultural Sciences (CAAS) 01.01.2019
Czech Academy of Agricultural Sciences
Subjects
Absorption
absorption of ca and mg
Calcium
Cecum
Diet
Evaluation
femur
Fermentation
Food industry
Food production
Magnesium
Mannitol
Nutrient deficiency
ovariectomized rat
Ovariectomy
Parameters
Pharmaceutical industry
Retention
Rodents
Sugar
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Summary:Indigestible sugars are used in food production and pharmaceutical industry due to their desirable properties. The effects of mannitol on Ca and Mg absorption and retention in ovariectomized rats were evaluated. Five weeks old ovariectomized Wistar rats were given Ca, Mg-deficient diet for 28 days then fed a control diet or 8% mannitol diets for another 28 days. Feaces were collected twice for 72h to measure mineral absorption. On day 56, rats were slaughtered and cecal parameters were observed. Femurs were collected to measure mineral levels. Results were shown that mineral absorption and femoral mineral was significantly increased by mannitol feeding. Cecal parameters were significantly altered after mannitol consumption. In conclusion, Ca and Mg absorption and their retention were improved by cecal fermentation of mannitol in ovariectomized rats.
ISSN:1212-1800
1805-9317
DOI:10.17221/420/2017-CJFS