Suspected familial renal disease in Chow Chows

Renal disease was diagnosed in 6 young Chow Chows. Clinical abnormalities included vomiting, polyuria, polydipsia, and weight loss. Common abnormal laboratory findings were azotemia, hyperphosphatemia, hypocalcemia, nonregenerative anemia, and low urine specific gravity. All 6 dogs had similar micro...

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Bibliographic Details
Published inJournal of the American Veterinary Medical Association Vol. 196; no. 8; p. 1279
Main Authors Brown, C.A. (University of Georgia, Athens, GA), Crowell, W.A, Brown, S.A, Barsanti, J.A, Finco, D.R
Format Journal Article
LanguageEnglish
Published United States 15.04.1990
Subjects
ANIMAL DISEASE SYMPTOMS
Animals
BREEDS
CASE STUDIES
CHIEN
Dog Diseases - genetics
DOGS
ENFERMEDADES RENALES
ESTUDIOS DE CASOS PRACTICOS
ETUDE DE CAS
FAMILIA
FAMILIES
FAMILLE
Female
HISTOPATHOLOGY
Kidney - pathology
KIDNEY DISEASES
Kidney Diseases - genetics
Kidney Diseases - veterinary
Kidney Failure, Chronic - genetics
Kidney Failure, Chronic - veterinary
Male
NEPHROPATHIE
Pedigree
PERRO
RACE
RAZAS
SINTOMAS DE ENFERMEDADES (ANIMALES)
SYMPTOME DE MALADIE ANIMALE
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Summary:Renal disease was diagnosed in 6 young Chow Chows. Clinical abnormalities included vomiting, polyuria, polydipsia, and weight loss. Common abnormal laboratory findings were azotemia, hyperphosphatemia, hypocalcemia, nonregenerative anemia, and low urine specific gravity. All 6 dogs had similar microscopic renal lesions. characterized by interstitial fibrosis, a population of small glomeruli, and lack of inflammatory cells. A familial basis for the renal disease is suggested because of its development in 4 closely related dogs.
Bibliography:L74
9033983
ISSN:0003-1488
1943-569X
DOI:10.2460/javma.1990.196.08.1279