2D materials as a diagnostic platform for the detection and sensing of the SARS-CoV-2 virus: a bird's-eye view
Worldwide infections and fatalities caused by the SARS-CoV-2 virus and its variants responsible for COVID-19 have significantly impeded the economic growth of many nations. People in many nations have lost their livelihoods, it has severely impacted international relations and, most importantly, hea...
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| Published in | Journal of materials chemistry. B, Materials for biology and medicine Vol. 9; no. 23; pp. 468 - 4619 |
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| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
England
Royal Society of Chemistry
16.06.2021
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| Subjects | |
| Online Access | Get full text |
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| Summary: | Worldwide infections and fatalities caused by the SARS-CoV-2 virus and its variants responsible for COVID-19 have significantly impeded the economic growth of many nations. People in many nations have lost their livelihoods, it has severely impacted international relations and, most importantly, health infrastructures across the world have been tormented. This pandemic has already left footprints on human psychology, traits, and priorities and is certainly going to lead towards a new world order in the future. As always, science and technology have come to the rescue of the human race. The prevention of infection by instant and repeated cleaning of surfaces that are most likely to be touched in daily life and sanitization drives using medically prescribed sanitizers and UV irradiation of textiles are the first steps to breaking the chain of transmission. However, the real challenge is to develop and uplift medical infrastructure, such as diagnostic tools capable of prompt diagnosis and instant and economic medical treatment that is available to the masses. Two-dimensional (2D) materials, such as graphene, are atomic sheets that have been in the news for quite some time due to their unprecedented electronic mobilities, high thermal conductivity, appreciable thermal stability, excellent anchoring capabilities, optical transparency, mechanical flexibility, and a unique capability to integrate with arbitrary surfaces. These attributes of 2D materials make them lucrative for use as an active material platform for authentic and prompt (within minutes) disease diagnosis
via
electrical or optical diagnostic tools or
via
electrochemical diagnosis. We present the opportunities provided by 2D materials as a platform for SARS-CoV-2 diagnosis.
This article reviews the use of two-dimensional materials as diagnostic platforms for the detection and sensing of the SARS-CoV-19 virus. |
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| Bibliography: | Dr Pranay Ranjan graduated from the Indian Institute of Technology Patna (IIT Patna) in 2019. During his doctoral training, he received an industrial award for making a methane gas sensor and, after completion of his graduation, he won Best PhD thesis award. He holds a Bachelor (BTech, Hons.) degree in Electronics and Communication Engineering. In 2020, he joined United Arab Emirates University as a Postdoctoral Researcher. His research interests include 2D materials and their hybrids, gas sensing, water desalination and filtration, and semiconductor devices. Prof. Vinoy Thomas is a Faculty and Graduate Program Director at the Department of Materials Science and Engineering, University of Alabama at Birmingham, USA. He holds secondary appointments in other UAB Departments; Physics (College of Arts and Sciences), Biomedical Engineering (School of Medicine-Engineering), and Environmental Health Sciences (School of Public Health). He is an Associate Scientist at the UAB Centre for Nanoscale Materials and Bio- integration (CNMB) and UAB Comprehesive Arthritis, Musculosketetal, Bone and Autoimmunity Center. After earned his PhD in Biomaterials and Technology, Prof. Thomas completed postdoctoral training at the University of Jena, Germany, and at the National Institute of Standards & Technology (NIST) USA [as NRC Fellow of the US National Academy of Sciences, (NAS)]. His research focuses on biomaterial processing-property relationships, nanomaterials for tissue engineering/drug delivery, plasma processing, 3D bioprinting and nanodiamonds for joint implants. He has more than 100 publications (h index = 30) and several published patents. Prof. Thomas is a recipient of the UAB provost award for Faculty Excellence and the UAB Graduate School Dean's award for Excellent Mentorship. He is a life-member/member of many professional societies and Vice-president of the Alabama Academy of Sciences (AAS), as well as serving as an editorial board member for several scientific journals in his area of research. Prof. Prashant Kumar received his doctorate in physics in April 2009 from the University of Hyderabad and worked with Prof. CNR. Rao at JNCASR Bangalore as a DST Nanoscience Postdoc until June 2012. He then worked as a Raytheon-funded Postdoc with Prof. Timothy S. Fisher at Purdue University, USA. From April 2013 onward, he worked as an NSF-funded Postdoc with Prof. Gary J Cheng at Purdue University. Being awarded a Ramanujan Fellowship, he started working at the Indian Institute of Technology Patna in June 2015. His research interests include novel synthetic strategies for 2D materials and their hybrids and doped nanosystems with emphasis on energy solutions. ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 |
| ISSN: | 2050-750X 2050-7518 |
| DOI: | 10.1039/d1tb00071c |