Liquid-liquid microflow reaction engineering

Microflow reaction is important for the miniaturization of chemical devices and systems. From an engineering perspective, excellent characteristics, including narrow residence time distribution, rapid reactant mixing, fast mass and heat transfer, and effective droplet morphology control, of segmente...

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Published inReaction chemistry & engineering Vol. 2; no. 5; pp. 611 - 627
Main Authors Wang, Kai, Li, Liantang, Xie, Pei, Luo, Guangsheng
Format Journal Article
LanguageEnglish
Published Cambridge Royal Society of Chemistry 01.01.2017
Subjects
Chemical reactions
Engineering
Fluid dynamics
Industrial applications
Liquid flow
Microfluidics
Miniaturization
Residence time distribution
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Summary:Microflow reaction is important for the miniaturization of chemical devices and systems. From an engineering perspective, excellent characteristics, including narrow residence time distribution, rapid reactant mixing, fast mass and heat transfer, and effective droplet morphology control, of segmented liquid-liquid flow in microspace are summarized in this review based on recent research progress in the areas of microfluidics, flow chemistry, micro total analysis, and microreaction engineering. Via engineering, important roles of segmented liquid-liquid flow, such as improvements in production yield, inline purification of intermediates and products, creative droplet reactors, and preparation of particle materials with various structures, are introduced. The scale-up of micro devices and large-scale production of chemicals through microflow technology are also discussed, showing good prospects in research and industrial application. Engineering characteristics of liquid-liquid microflow and its advantages in chemical reactions.
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ISSN:2058-9883
2058-9883
DOI:10.1039/c7re00082k