Saringosterol Acetate Isolated from Sargassum fusiformis Induces Mitochondrial‐Mediated Apoptosis in MCF‐7 Breast Cancer Cells

• Published in: Chemistry & biodiversity Vol. 19; no. 3; pp. e202100848 - n/a
• Main Authors: Li, Xue, Zhou, Dong‐Yue, Li, Fang‐Tong, Jiang, Yun‐Fei, Dai, Yu‐Lin, Jeon, You‐Jin
• Format: Journal Article
• Language: English
• Published: Switzerland Wiley Subscription Services, Inc 01.03.2022
• Subjects: Acetates - pharmacology; Acetic acid; Algae; anticancer effect; Anticancer properties; Apoptosis; Bioactive compounds; Breast cancer; Breast Neoplasms - drug therapy; Caspase-3; Drug development; Female; Humans; MCF-7 Cells; Mitochondria; mitochondria-mediated pathway; Sargassum; Sargassum fusiformis; saringosterol acetate; Seaweeds; Stigmasterol - analogs & derivatives; Survival; Sargassum fusiformis; mitochondria-mediated pathway; saringosterol acetate; anticancer effect

Sargassum fusiformis is among the most important edible brown seaweeds in Eastern Asia that contains various bioactive compounds and strong activities. Saringosterol acetate (SA) was successfully isolated from S. fusiformis in our previous research. In this study, SA was investigated for its antican...