2D MXene Nanomaterials for Versatile Biomedical Applications: Current Trends and Future Prospects

Research on 2D nanomaterials is still in its early stages. Most studies have focused on elucidating the unique properties of the materials, whereas only few reports have described the biomedical applications of 2D nanomaterials. Recently, important questions about the interaction of 2D MXene nanomat...

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Published inSmall (Weinheim an der Bergstrasse, Germany) Vol. 17; no. 46; pp. e2100946 - n/a
Main Authors Lu, Beibei, Zhu, Zhenye, Ma, Biyuan, Wang, Wei, Zhu, Rongshu, Zhang, Jiaheng
Format Journal Article
LanguageEnglish
Published Germany Wiley Subscription Services, Inc 01.11.2021
Subjects
Anti-Bacterial Agents - pharmacology
Biocompatibility
biological applications
Biomedical materials
compatibility
Drug Delivery Systems
Medical imaging
MXenes
Nanomaterials
nanomedicines
Nanostructure
Nanostructures
Nanotechnology
surface modification
Trends
biological applications
compatibility
nanomedicines
surface modification
MXenes
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Summary:Research on 2D nanomaterials is still in its early stages. Most studies have focused on elucidating the unique properties of the materials, whereas only few reports have described the biomedical applications of 2D nanomaterials. Recently, important questions about the interaction of 2D MXene nanomaterials with biological components have been raised. 2D MXenes are monolayer atomic nanosheets derived from MAX phase ceramics. As a new type of inorganic nanosystems, they are being widely used in biology and biomedicine. This review introduces the latest developments in 2D MXenes for the most advanced biomedical applications, including preparation and surface modification strategies, treatment modes, drug delivery, antibacterial activity, bioimaging, sensing, and biocompatibility. Besides, this review also discusses the current development trends and prospects of 2D inorganic nanosheets for further clinical applications. These emerging 2D inorganic MXenes will play an important role in next‐generation cancer treatments. In this review, the exfoliated method and application of MXene are summarized, especially the ionic liquid exfoliation of MXene, which is a new green, nontoxic and safe method and has great application potential in the medical field, such as photothermal therapy, photodynamic therapy, drug delivery, bioimaging, and antibacterial activity. Therefore, MXene materials have prospects in the field of medicine.
ISSN:1613-6810
1613-6829
DOI:10.1002/smll.202100946