Antibacterial Carbon Dots‐Based Composites

• Published in: Small (Weinheim an der Bergstrasse, Germany) Vol. 19; no. 31; pp. e2207385 - n/a
• Main Authors: Huang, Shan, Song, Yuexin, Zhang, Jian‐Rong, Chen, Xiaojun, Zhu, Jun‐Jie
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 01.08.2023
• Subjects: Anti-Bacterial Agents - pharmacology; Anti-Infective Agents; antibacterial; Antibiotics; Antiinfectives and antibacterials; Biocompatibility; Carbon; Carbon dots; carbon dots‐based composites; Composite materials; Infectious diseases; membrane disruption; Nanomaterials; Nanostructures; Nanotechnology; oxidative stress; Quantum Dots; carbon dots; antibacterial; membrane disruption; carbon dots-based composites; oxidative stress
• ISSN: 1613-6810; 1613-6829; 1613-6829
• DOI: 10.1002/smll.202207385

The emergence and global spread of bacterial resistance to conventionally used antibiotics have highlighted the urgent need for new antimicrobial agents that might replace antibiotics. Currently, nanomaterials hold considerable promise as antimicrobial agents in anti‐inflammatory therapy. Due to their distinctive functional physicochemical characteristics and exceptional biocompatibility, carbon dots (CDs)‐based composites have attracted a lot of attention in the context of these antimicrobial nanomaterials. Here, a thorough assessment of current developments in the field of antimicrobial CDs‐based composites is provided, starting with a brief explanation of the general synthesis procedures, categorization, and physicochemical characteristics of CDs‐based composites. The many processes driving the antibacterial action of these composites are then thoroughly described, including physical destruction, oxidative stress, and the incorporation of antimicrobial agents. Finally, the obstacles that CDs‐based composites now suffer in combating infectious diseases are outlined and investigated, along with the potential applications of antimicrobial CDs‐based composites. Carbon dots (CDs)‐based composites integrate the outstanding properties of functional modules and CDs, exhibiting remarkable optical, enzyme‐like activity, and biocompatible properties, emerging as a promising application tool in the field of bacteriostatic therapy.