It’s time to think about circadian rhythms

Summary We here introduce a Review Series focussing on the important influences circadian rhythms have on immune responses. The three reviews in this series, expertly curated by Rachel Edgar, discuss how the cyclic oscillations in our cellular clock affect the innate and adaptive immune response, an...

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Bibliographic Details
Published inImmunology Vol. 161; no. 4; pp. 259 - 260
Main Author Milling, Simon
Format Journal Article
LanguageEnglish
Published England Wiley Subscription Services, Inc 01.12.2020
John Wiley and Sons Inc
Subjects
Adaptive Immunity
Animals
Autoimmunity
Biological clocks
Biological Clocks - immunology
Circadian Rhythm - immunology
Circadian rhythms
Gastrointestinal Microbiome - immunology
Humans
Immune response
Immune system
Immunity, Innate
Immunology
Intestinal microflora
Intestine
Microbiota
Oscillations
Review Series: Circadian rhythms for immunologists
Vaccination
Vaccines - immunology
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Summary:Summary We here introduce a Review Series focussing on the important influences circadian rhythms have on immune responses. The three reviews in this series, expertly curated by Rachel Edgar, discuss how the cyclic oscillations in our cellular clock affect the innate and adaptive immune response, and how interactions with the intestinal microbiota, themselves subject to daily oscillations, also influence immune responses. As we understand more about these mechanisms, by which chronobiology contributes to immunology, it is becoming increasingly clear that they have important functions in maintaining health, influence autoimmunity and may contribute to the effectiveness of vaccinations.
Bibliography:Circadian rhythms in adaptive immunity. Immunology 2020, 161: 268‐277.
Crosstalk between circadian rhythms and the microbiota. Immunology 2020, 161: 278‐290.
OTHER ARTICLES PUBLISHED IN THIS REVIEW SERIES
Circadian rhythms in innate immunity and stress responses. Immunology 2020, 161: 261‐267
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ISSN:0019-2805
1365-2567
1365-2567
DOI:10.1111/imm.13284