Dimensional Reduction of Metal–Organic Frameworks for Enhanced Cryopreservation of Red Blood Cells

• Published in: Angewandte Chemie International Edition Vol. 62; no. 22; pp. e202217374 - n/a
• Main Authors: Lei, Qi, Sun, Yaqian, Huang, Junda, Liu, Wei, Zhan, Xiaolong, Yin, Wenxiang, Guo, Sishi, Sinelshchikova, Anna, Brinker, C. Jeffrey, He, Zhiyuan, Guo, Jimin, Wuttke, Stefan, Zhu, Wei
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 22.05.2023
• Edition: International ed. in English
• Subjects: Cryopreservation; Cryopreservation - methods; Cryoprotective Agents - chemistry; Cryoprotective Agents - pharmacology; Cryoprotectors; Dimensional Reduction; Erythrocytes; Hafnium; Hafnium - chemistry; Hydrogen bonding; Hydrogen Bonding Matching; Ice; Ice-Inhibition; Metal-organic frameworks; Metal-Organic Frameworks - chemistry; Multilayers; Nanoparticles; Recrystallization; Red Blood Cell Cryopreservation; Reduction (metal working); Thin films; Hydrogen Bonding Matching; Metal-Organic Frameworks; Dimensional Reduction; Red Blood Cell Cryopreservation; Ice-Inhibition

To increase the red blood cell (RBC) cryopreservation efficiency by metal–organic frameworks (MOFs), a dimensional reduction approach has been proposed. Namely, 3D MOF nanoparticles are progressively reduced to 2D ultra‐thin metal–organic layers (MOLs). We found that 2D MOLs are beneficial for enhan...