Anti‐Inflammatory Phomalones from the Deep‐Sea‐Derived Fungus Trichobotrys effuse FS522

• Published in: Chemistry & biodiversity Vol. 20; no. 12; pp. e202301512 - n/a
• Main Authors: Huang, Hui‐Bin, Chen, Yu‐Chan, Wen, Ting‐Yue, Li, Sai‐Ni, Liu, Zhao‐Ming, Zhang, Wei‐Min, Gao, Xiao‐Xia
• Format: Journal Article
• Language: English
• Published: Switzerland Wiley Subscription Services, Inc 01.12.2023
• Subjects: anti-inflammatory; Anti-Inflammatory Agents - pharmacology; Ascomycota; Circular dichroism; deep-sea-derived fungus; Dichroism; Fungi; Heterocyclic Compounds, 3-Ring - chemistry; Heterocyclic Compounds, 3-Ring - pharmacology; Inflammation; Magnetic Resonance Spectroscopy - methods; Molecular Structure; Nitric oxide; NMR; Nuclear magnetic resonance; phomalones; Pyrans - chemistry; Pyrans - pharmacology; spectroscopic analysis; Trichobotrys effuse; anti-inflammatory; spectroscopic analysis; phomalones; Trichobotrys effuse; deep-sea-derived fungus

Four new phomalones A−D (1–4), together with five known analogues (5–9) were isolated from the deep‐sea‐derived fungus Trichobotrys effuse FS522. Their structures of the new compounds established by analysis of their NMR and HR‐ESI‐MS spectroscopic data, and the absolute configurations of 2 was dete...