Ultrasensitive, Rapid, and Selective Detection of Mercury Using Graphene Assisted Laser Desorption/Ionization Mass Spectrometry

We report an extremely sensitive and specific detection of mercuric ions (Hg 2+ ) based on graphene assisted laser desorption/ionization mass spectrometry (GALDI-MS). Combining the highly selective coordination interactions between thymine (T) and Hg 2+ , we present a simple, effective, and novel ap...

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Bibliographic Details
Published inJournal of the American Society for Mass Spectrometry Vol. 25; no. 5; pp. 861 - 868
Main Authors Abdelhamid, Hani Nasser, Wu, Hui-Fen
Format Journal Article
LanguageEnglish
Published Boston Springer US 01.05.2014
Springer Nature B.V
Subjects
Analytical Chemistry
Bioinformatics
Biotechnology
Chemistry
Chemistry and Materials Science
Coordination Complexes - chemistry
Coordination compounds
Desorption
Environmental Pollutants - analysis
Environmental Pollutants - chemistry
Graphene
Graphite - chemistry
Indicators and Reagents - chemistry
Ionization
Ions
Limit of Detection
Mass spectrometry
Mercury (metal)
Mercury - analysis
Mercury - chemistry
Mercury Compounds - analysis
Mercury Compounds - chemistry
Microchemistry - methods
Microscopy, Electron, Transmission
Molecular Structure
Nanostructures - chemistry
Organic Chemistry
Pretreatment
Proteomics
Reproducibility of Results
Research Article
Scientific imaging
Selectivity
Solubility
Spectrometry, Mass, Secondary Ion
Spectroscopy
Thymine
Thymine - chemistry
Time Factors
Graphene
Mass spectrometry
Mercury
Selective
Biosensing
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Summary:We report an extremely sensitive and specific detection of mercuric ions (Hg 2+ ) based on graphene assisted laser desorption/ionization mass spectrometry (GALDI-MS). Combining the highly selective coordination interactions between thymine (T) and Hg 2+ , we present a simple, effective, and novel approach, based on π–π interactions of the T-Hg 2+ -T complex and G that can serve as a platform and matrix for GALDI-MS. The present sensor not only exhibits high selectivity and sensitivity (picomolar) to Hg 2+ in aqueous solution, but also can elucidate the chemical structures of the metal complexes. The significant advantage in the current approach is that there is no need for a sophisticated instrument, and no sample pretreatment is required to detect the Hg 2+ ions. Figure ᅟ
ISSN:1044-0305
1879-1123
DOI:10.1007/s13361-014-0825-z