Exploring the cell nucleus: From chromosome structure to single-cell omics

The cell nucleus is a fascinating organelle. The myriad of fundamental processes that ensure that the genetic information is read correctly and faithfully transmitted provides a rich subject of research across time scales and model systems. Topics ranging from chromosome ‘metascale’ organization and...

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Published inCurrent opinion in cell biology Vol. 95; p. 102530
Main Authors Fukagawa, Tatsuo, Torres-Padilla, Maria Elena
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.08.2025
Subjects
Animals
Cell Nucleus - genetics
Cell Nucleus - metabolism
Chromosomes - genetics
Chromosomes - metabolism
Genomics
Humans
Single-Cell Analysis
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Summary:The cell nucleus is a fascinating organelle. The myriad of fundamental processes that ensure that the genetic information is read correctly and faithfully transmitted provides a rich subject of research across time scales and model systems. Topics ranging from chromosome ‘metascale’ organization and division, enabled by molecular machineries like the kinetochore, to the organization of the genome that ensues cell division during interphase, which enables fine tuning of gene regulation, are subjects that we cover in the ‘Cell Nucleus’ issue of Current Opinion in Cell Biology.
Bibliography:SourceType-Scholarly Journals-1
content type line 23
ObjectType-Editorial-2
ObjectType-Commentary-1
ISSN:0955-0674
1879-0410
1879-0410
DOI:10.1016/j.ceb.2025.102530