T-705 (Favipiravir) Induces Lethal Mutagenesis in Influenza A H1N1 Viruses In Vitro

• Published in: Journal of Virology Vol. 87; no. 7; pp. 3741 - 3751
• Main Authors: Baranovich, Tatiana, Wong, Sook-San, Armstrong, Jianling, Marjuki, Henju, Webby, Richard J., Webster, Robert G., Govorkova, Elena A.
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 01.04.2013
• Subjects: Amides - pharmacology; Analysis of Variance; Animals; Antiviral Agents - pharmacology; Dogs; Drug Discovery - methods; In Vitro Techniques; Influenza A Virus, H1N1 Subtype - drug effects; Influenza A Virus, H1N1 Subtype - genetics; Influenza A Virus, H1N1 Subtype - pathogenicity; Madin Darby Canine Kidney Cells; Mutagenesis - drug effects; Mutagenesis - genetics; Orthomyxoviridae Infections - drug therapy; Pyrazines - pharmacology; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Vaccines and Antiviral Agents
• ISSN: 0022-538X; 1098-5514; 1098-5514
• DOI: 10.1128/JVI.02346-12

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