Influence of early-life and parental factors on childhood overweight and obesity

• Published in: Journal of endocrinological investigation Vol. 39; no. 11; pp. 1315 - 1321
• Main Authors: Parrino, C., Vinciguerra, F., La Spina, N., Romeo, L., Tumminia, A., Baratta, R., Squatrito, S., Vigneri, R., Frittitta, L.
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.11.2016; Springer Nature B.V
• Subjects: Adolescent; Birth Weight; Body weight; Breast feeding; Child; Children; Cross-Sectional Studies; Endocrinology; Environment; Environmental factors; Feeding and Eating Disorders of Childhood - physiopathology; Female; Health risk assessment; Humans; Italy - epidemiology; Male; Males; Medicine; Medicine & Public Health; Metabolic Diseases; Neonates; Obesity; Original Article; Overweight; Overweight - epidemiology; Pediatric Obesity - epidemiology; Prevalence; Risk Factors; Sex differences; Surveys and Questionnaires; Obesity risk factors; Birth weight; Education level; Breastfeeding
• ISSN: 1720-8386; 0391-4097; 1720-8386
• DOI: 10.1007/s40618-016-0501-1

Purpose We recently reported that a high BMI and high waist circumference prevalence is present in Sicilian children and that the male gender is associated with a significant risk of obesity. Early-life and parent-related risk factors were investigated 1521 Sicilian children (752 females and 769 males, aged 9.0–14.0 years) to identify biological and environmental factors that can contribute to obesity onset. Methods Anthropometric measurements of children, their urban vs rural area provenience, birth weight and neonatal feeding were collected. In addition, the BMI and educational level of their parents and the perception of their child weight status were investigated. Results In the study cohort, the prevalence of overweight and obesity was 27.2 and 14.1 %, respectively, significantly ( p  < 0.05) higher in males than in females. Breastfeeding emerged as a protective factor (OR 0.64; p  < 0.0005), while risk factors for developing childhood obesity were a birth weight ≥4.0 kg (OR 1.83; p  < 0.05), an overweight or obese mother (OR 2.33; p  < 0.0001) or father (OR 1.68; p  < 0.0001) and a mother with a low/medium education level (OR 1.72; p  < 0.005). Conclusion Understanding risk factors for pediatric obesity is a prerequisite to identify children at highly risk of being obese and to predispose early intervention strategies.