Bone and wound healing augmentation with platelet-rich plasma

Over the past two decades, autologous platelets that have been sequestered, concentrated, and mixed with thrombin to generate growth factor-concentrated platelet-rich plasma for application to bone and wounds to aide healing have been a subject of great interest. This article reviews the literature...

Full description

Saved in:
Bibliographic Details
Published inClinics in podiatric medicine and surgery Vol. 26; no. 4; p. 559
Main Authors Smith, Simon E, Roukis, Thomas S
Format Journal Article
LanguageEnglish
Published United States 01.10.2009
Subjects
Animals
Bone and Bones - injuries
Bone and Bones - surgery
Cartilage - injuries
Cartilage - surgery
Guided Tissue Regeneration
Humans
Intercellular Signaling Peptides and Proteins - pharmacology
Oral Surgical Procedures
Orthopedic Procedures
Platelet-Rich Plasma
Tendon Injuries - surgery
Transplantation, Autologous
Wound Healing
Online AccessGet more information

Cover

More Information
Summary:Over the past two decades, autologous platelets that have been sequestered, concentrated, and mixed with thrombin to generate growth factor-concentrated platelet-rich plasma for application to bone and wounds to aide healing have been a subject of great interest. This article reviews the literature related to the use of autologous platelet-rich plasma in bone and wound healing, and reviews the processes necessary to secure a high concentration of viable platelets. Although not yet definitive, autologous platelet-rich plasma has been shown to be safe, reproducible, and effective in mimicking the natural process of bone and wound healing.
ISSN:1558-2302
DOI:10.1016/j.cpm.2009.07.002