Follicular Thyroid Carcinoma with Signet Ring Cell Morphology: Fine-Needle Aspiration Cytology, Histopathology, and Immunohistochemistry

Thyroid follicular neoplasms with signet ring cell morphology represent a challenging cytological and histopathologic diagnosis. The low frequency of these neoplasms and their broad differential diagnosis contribute to this difficult scenario. Here, we present an exceptionally rare case of thyroid f...

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Bibliographic Details
Published inEndocrine pathology Vol. 24; no. 4; pp. 239 - 245
Main Authors Romero-Rojas, Alfredo E., Diaz-Perez, Julio A., Mastrodimos, Melina, Chinchilla, Sandra I.
Format Journal Article
LanguageEnglish
Published Boston Springer US 01.12.2013
Springer Nature B.V
Subjects
Adenocarcinoma, Follicular - metabolism
Adenocarcinoma, Follicular - pathology
Biomarkers, Tumor - metabolism
Biopsy, Fine-Needle
Endocrinology
Female
Humans
Immunohistochemistry
Medicine
Medicine & Public Health
Middle Aged
Oncology
Pathology
Thyroid Neoplasms - metabolism
Thyroid Neoplasms - pathology
Signet ring cell
Histopathology
Follicular thyroid carcinoma
Cytology
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Summary:Thyroid follicular neoplasms with signet ring cell morphology represent a challenging cytological and histopathologic diagnosis. The low frequency of these neoplasms and their broad differential diagnosis contribute to this difficult scenario. Here, we present an exceptionally rare case of thyroid follicular carcinoma with signet ring cell morphology in a 62-year-old female. We analyze the characteristics in fine-needle aspiration cytology, histopathology, and immunohistochemistry and compare our results in a discussion with previous literature reports.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
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ISSN:1046-3976
1559-0097
DOI:10.1007/s12022-013-9271-x