Kinematic Outcome Measures using Target-Reaching Arm Movement in Stroke

• Published in: Annals of biomedical engineering Vol. 45; no. 12; pp. 2794 - 2803
• Main Authors: Yang, Qianqian, Yang, Yuan, Luo, Jie, Li, Le, Yan, Tiebin, Song, Rong
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.12.2017; Springer Nature B.V
• Subjects: Arm; Arm - physiopathology; Biochemistry; Biological and Medical Physics; Biomedical and Life Sciences; Biomedical Engineering and Bioengineering; Biomedicine; Biophysics; Classical Mechanics; Diagnostic Techniques, Neurological; Elbow; Elbow (anatomy); Entropy; Female; Humans; Kinematics; Male; Middle Aged; Motor task performance; Movement; Movement Disorders - diagnosis; Movement Disorders - etiology; Movement Disorders - physiopathology; Outcome Assessment (Health Care) - methods; Patients; Physical Examination - methods; Psychomotor Performance; Reproducibility of Results; Sensitivity and Specificity; Stroke; Stroke - complications; Stroke - diagnosis; Stroke - physiopathology; Velocity; Stroke; Target-reaching; Motor control; Joint synergy; Kinematics
• ISSN: 0090-6964; 1573-9686; 1573-9686
• DOI: 10.1007/s10439-017-1912-7

This study aimed to quantitatively investigate upper extremity motor performance and disclose the abnormality of motor control induced by stroke. Ten patients and ten healthy subjects were instructed to perform target-reaching tasks at nine difficulty levels, and coordinates of the shoulder, elbow and tip of the index finger were recorded. Age-matched control performed significantly better than patients, as indicated by lower movement time (MT) and normalized jerk score (NJS) and higher peak velocity ( V peak ), percentage time to peak velocity (PTPV), fuzzy approximate entropy (fApEn) and relative joint angles correlation (RJAC); also, significant effects of difficulty on all parameters except RJAC and fApEn, were observed in two groups. There were significant correlations between PTPV and Fugl-Meyer assessment for upper extremity (FMA-UE) and between RJAC and FMA-UE at certain difficulty levels. The stroke-related differences could be explained by the increase in intrinsic neuromotor noise, and the difficulty-related differences may be related to extrinsic neuromotor noise. The increase in either noises could result in a degradation in motor control. The significant linear relationships between some kinematic parameters and the clinical score suggested that the kinematic parameters could be applied as quantitative outcome measures in the clinic in the future.