Kawasaki disease: a review with emphasis on cardiovascular complications

Kawasaki disease (KD) is an acute systemic vasculitis that is currently the leading cause of acquired heart disease in childhood in the United States. Cardiovascular complications are the major cause of morbidity, are responsible for virtually all deaths from KD and should be evaluated as soon as po...

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Published inInsights into imaging Vol. 1; no. 4; pp. 223 - 231
Main Authors Duarte, Ricardo, Cisneros, Silvia, Fernandez, Gabriel, Castellon, Daniel, Cattani, Cesar, A Melo, Cíntia, Apocada, Asier
Format Journal Article
LanguageEnglish
Published Berlin/Heidelberg Springer Berlin Heidelberg 01.09.2010
Springer-Verlag
Subjects
Diagnostic Radiology
Imaging
Internal Medicine
Interventional Radiology
Medicine
Medicine & Public Health
Neuroradiology
Radiology
Review
Ultrasound
Acute vasculitis
Kawasaki disease
Cardiovascular complications
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Summary:Kawasaki disease (KD) is an acute systemic vasculitis that is currently the leading cause of acquired heart disease in childhood in the United States. Cardiovascular complications are the major cause of morbidity, are responsible for virtually all deaths from KD and should be evaluated as soon as possible after the acute phase to establish the baseline status, in order to predict disease progression and determine adequate treatment. In selected patients, electrocardiography (ECG)-gated cardiac computed tomography (CT) and magnetic resonance (MR) imaging are valuable non-invasive techniques that can be used to help diagnose the cardiovascular complications associated with KD. In this article, we review the epidemiology, aetiology and pathogenesis, histopathology, clinical features, cardiovascular complications and imaging, focusing on the role of cardiac CT and MR on the initial assessment and follow-up of the cardiovascular complications of KD.
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ISSN:1869-4101
1869-4101
DOI:10.1007/s13244-010-0035-6