Hypertension associated with massive, bilateral, posture-dependent renal dysfunction

• Published in: Radiology Vol. 140; no. 1; p. 231
• Main Authors: Clorius, J H, Schmidlin, P, Raptou, E, Huber, W, Georgi, P
• Format: Journal Article
• Language: English
• Published: United States 01.07.1981
• Subjects: Hippurates - metabolism; Humans; Hypertension - complications; Hypertension - diagnostic imaging; Hypertension - metabolism; Kidney Diseases - complications; Kidney Diseases - diagnostic imaging; Kidney Diseases - metabolism; Kidney Tubules - diagnostic imaging; Kidney Tubules - metabolism; Kidney Tubules - physiopathology; Posture; Radiography; Radioisotope Renography
• ISSN: 0033-8419
• DOI: 10.1148/radiology.140.1.7244230

Hippurate function scintiscans were obtained in prone and standing positions in a group of 76 patients with concurrent hypertension and nephroptosis. TWelve of these patients had massive, bilateral disturbance of intrarenal hippurate transport in the standing position; hippurate transport was normal in the prone position. This pattern was present in only three of 120 normotensive patients with nephroptosis. To investigate the importance of nephroptosis, 87 other hypertensive patients were examined. Eighteen of these patients demonstrated posture-dependent tubular dysfunction, but only four had nephroptosis. The results suggest a direct relationship between bilateral posture-dependent tubular dysfunction and hypertension.