Clara Maass, Yellow Fever and Human Experimentation

Clara Louise Maass, a 25-year-old American nurse, died of yellow fever on August 24, 1901, following experimental inoculation by infected mosquitoes in Havana, Cuba. The human yellow fever experiments were initially conducted by MAJ Walter Reed, who first used written informed consent and proved the...

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Bibliographic Details
Published inMilitary medicine Vol. 178; no. 5; pp. 557 - 562
Main Author Chaves-Carballo, Enrique
Format Journal Article
LanguageEnglish
Published England Oxford University Press 01.05.2013
Subjects
Clara Louise Maass
History of Nursing
History, 19th Century
History, 20th Century
Human Experimentation - history
Humans
Maass Clara Louise
United States
Yellow Fever - history
United States
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Summary:Clara Louise Maass, a 25-year-old American nurse, died of yellow fever on August 24, 1901, following experimental inoculation by infected mosquitoes in Havana, Cuba. The human yellow fever experiments were initially conducted by MAJ Walter Reed, who first used written informed consent and proved the validity of Finlay's mosquito-vector hypothesis. Despite informed consent form and an incentive of $100 in U.S. gold, human subjects were exposed to a deadly virus. The deaths of Clara Maass and two Spanish immigrants resulted in a public outcry and the immediate cessation of yellow fever human experiments in Cuba.
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ISSN:0026-4075
1930-613X
1930-613X
DOI:10.7205/MILMED-D-12-00430