Efficiency and measurements agreement between swept-source OCT and low-coherence interferometry biometry systems

• Published in: Graefe's archive for clinical and experimental ophthalmology Vol. 256; no. 3; pp. 559 - 566
• Main Authors: Calvo-Sanz, Jorge A., Portero-Benito, Alejandro, Arias-Puente, Alfonso
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.03.2018; Springer Nature B.V
• Subjects: Aged; Aged, 80 and over; Agreements; Anterior chamber; Axial Length, Eye - diagnostic imaging; Biometry - methods; Cataract; Cataract - diagnosis; Cataracts; Cornea; Corneal Pachymetry; Eye; Eye lens; Female; Humans; Interferometry; Interferometry - methods; Male; Medicine; Medicine & Public Health; Middle Aged; Ophthalmology; Prospective Studies; Reproducibility of Results; ROC Curve; Statistical analysis; Tomography, Optical Coherence - methods; Cataract; IOLMaster; Aladdin; Biometry
• ISSN: 0721-832X; 1435-702X; 1435-702X
• DOI: 10.1007/s00417-018-3909-9

Purpose To compare and evaluate the agreement between the measurements obtained with a swept-source optical coherence tomography (OCT)-based biometer, the IOLMaster® 700 (IOLM), and those obtained by an optical biometer based on optical low-coherence interferometry (OLCI), the Aladdin (ALD); To evaluate the ability to perform biometric measurements in those eyes with transparency alterations. Methods Fifty-five eyes of 55 subjects were included in this study. Axial length (AL), corneal power (K, in diopters) and its astigmatism, anterior chamber depth (ACD), central corneal thickness (CCT), and lens thickness (LT) measures were obtained within both biometers, Zeiss IOLMaster 700 and Topcon Aladdin. Results were analyzed and compared using the Student’s paired samples t -test, Bland–Altman analysis and intraclass correlation coefficient (ICC). Results Mean age was 73.12 ± 2.63 (62–89 years). The IOLM mean AL, K, and LT values did not show a statistically significant difference from ALD values and showed excellent agreement and correlation (ICC = 1.000, 0.970, 0.952). IOLM measured a lower mean ACD (−0.036 mm) and higher CCT measurements (9.296 μm). Those results were statistically different ( p  < 0.001 in both cases) but showed an excellent correlation coefficients (ICC = 0.994, 0.938). IOLM was able to obtain measures from all the eyes examined, while ALD did not measure in two cases with dense nuclear cataract. ALD showed spherical K measures in 7.27% of cases. Conclusion Overall a quite good agreement between IOLM and ALD was found. ALD showed spherical keratometry measures in 7.27% of cases. IOLMaster 700 was more effective in obtaining AL measurements in eyes with dense cataracts.