Cyclobutane ring formation by triflic imide catalyzed [2+2]-cycloaddition of allylsilanes
Cyclobutane forming [2+2]-cycloaddition reactions of allylsilane with electron-deficient olefin is promoted by triflic imide (Tf 2NH). Cyclobutane forming [2+2]-cycloaddition reactions of allylsilane with electron-deficient olefin is promoted by triflic imide (Tf 2NH). Triflic imide is converted in...
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Published in | Tetrahedron letters Vol. 47; no. 34; pp. 6053 - 6056 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
OXFORD
Elsevier Ltd
21.08.2006
Elsevier |
Subjects | |
Online Access | Get full text |
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Summary: | Cyclobutane forming [2+2]-cycloaddition reactions of allylsilane with electron-deficient olefin is promoted by triflic imide (Tf
2NH).
Cyclobutane forming [2+2]-cycloaddition reactions of allylsilane with electron-deficient olefin is promoted by triflic imide (Tf
2NH). Triflic imide is converted in situ to silyl triflic imide (R
3SiNTf
2), which serves as the actual catalyst for this process. When these reactions take place at higher than ambient temperatures, thermodynamically more stable
anti-cyclobutanes are generated preferentially by equilibration of the initially formed adducts via retro [2+2]-cycloaddition. |
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ISSN: | 0040-4039 1873-3581 |
DOI: | 10.1016/j.tetlet.2006.06.102 |