Comparison of the circulatory effects of epinephrine and norepinephrine

A comparison was made of the circulatory effects of l -epinephrine and l -norepinephrine when various doses were given either intravenously or intra-arterially into anesthetized animals. No significant difference was found between the effects of identical doses of the two drugs on the arterial blood...

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Bibliographic Details
Published inCirculation (New York, N.Y.) Vol. 5; no. 3; pp. 370 - 379
Main Authors WAKIM, K G, ESSEX, H E
Format Journal Article
LanguageEnglish
Published United States 01.03.1952
Subjects
Blood Circulation - drug effects
Epinephrine - pharmacology
Humans
Norepinephrine - pharmacology
Old Medline
ARTERENOL/effects
EPINEPHRINE/effects
BLOOD CIRCULATION/effect of drugs on
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Summary:A comparison was made of the circulatory effects of l -epinephrine and l -norepinephrine when various doses were given either intravenously or intra-arterially into anesthetized animals. No significant difference was found between the effects of identical doses of the two drugs on the arterial blood pressure, heart rate and blood flow. The intensity and duration of effect of either drug varied roughly with the dose given.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0009-7322
1524-4539
DOI:10.1161/01.CIR.5.3.370