Physical activity in women with subclinical hypothyroidism

• Published in: Journal of endocrinological investigation Vol. 42; no. 7; pp. 779 - 785
• Main Authors: Tanriverdi, A., Ozcan Kahraman, B., Ozsoy, I., Bayraktar, F., Ozgen Saydam, B., Acar, S., Ozpelit, E., Akdeniz, B., Savci, S.
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.07.2019; Springer Nature B.V
• Subjects: Activities of Daily Living; Adult; Case-Control Studies; Cross-Sectional Studies; Endocrinology; Exercise; Female; Follow-Up Studies; Health risk assessment; Humans; Hypothyroidism; Hypothyroidism - blood; Hypothyroidism - physiopathology; Medicine; Medicine & Public Health; Metabolic Diseases; Muscle strength; Muscle, Skeletal - physiopathology; Original Article; Physical activity; Physical fitness; Physical training; Prognosis; Pulse Wave Analysis; Quadriceps muscle; Thyroid Hormones - blood; Women; Six-minute walk test; Physical activity; Arterial stiffness; Subclinical hypothyroidism
• ISSN: 1720-8386; 0391-4097; 1720-8386
• DOI: 10.1007/s40618-018-0981-2

Purpose Physical activity is associated with many health-related benefits. However, there is a shift towards inactive lifestyles around the world. Subclinical hypothyroidism (SCH) may have adverse effects similar to hypothyroidism. The presence of symptoms and reduced physical performance in SCH may contribute to an inactive lifestyle. Therefore, the present study aimed to compare physical activity levels (PALs) between women with subclinical hypothyroidism and healthy controls. Methods Thirty-two women with newly diagnosed SCH and 28 healthy women were enrolled in this cross-sectional study. Arterial stiffness was evaluated by pulse wave velocity (PWV). Neuromuscular symptoms were questioned. Participants wore a physical activity monitor (SenseWear ® Armband) for 4 consecutive days. Handgrip and quadriceps muscle strength were assessed by dynamometer. Functional exercise capacity was assessed by 6-minute walk test (6MWT). Results There was no significant difference in sociodemographic variables between the groups. PWV was significantly higher in the SCH group ( P  = 0.006). Physical activity duration and number of steps were significantly lower in the SCH group ( P  < 0.05). There was significant difference in neuromuscular symptoms, handgrip and quadriceps muscle strength, and 6MWT distance between the groups ( P  < 0.05). Conclusions This study demonstrates that women with SCH had lower PALs compared to healthy controls. Women with SCH should participate in exercise programs to increase physical activity and muscle strength to achieve adequate PALs.