Severe ischemic cytomegalovirus proctocolitis with multiple perforation

Cytomegalovirus (CMV) typically causes gastrointestinal infections in immunocompetent patients. Colonic perforations secondary to CMV are exceeding rare. We describe a 88-year-old male presenting with a week-long history of intractable abdominal discomfort, bloating, nausea and diarrhea. Flexible si...

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Bibliographic Details
Published inArchives of virology Vol. 163; no. 7; pp. 1927 - 1931
Main Authors D’cruz, Reuban Toby, Lau, Cheryl Chien-Li, Thamboo, Thomas Paulraj
Format Journal Article
LanguageEnglish
Published Vienna Springer Vienna 01.07.2018
Springer Nature B.V
Subjects
Biomedical and Life Sciences
Biomedicine
Brief Report
Colitis
Colon
Cytomegalovirus
Diarrhea
Differential diagnosis
Infections
Infectious Diseases
Ischemia
Medical Microbiology
Nausea
Sigmoidoscopy
Surgery
Vasculitis
Virology
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Summary:Cytomegalovirus (CMV) typically causes gastrointestinal infections in immunocompetent patients. Colonic perforations secondary to CMV are exceeding rare. We describe a 88-year-old male presenting with a week-long history of intractable abdominal discomfort, bloating, nausea and diarrhea. Flexible sigmoidoscopy revealed significant ulceration with yellowish slough. Emergency surgery was performed subsequently in view of multiple perforations in the rectosigmoid junction. CMV gastrointestinal infections demonstrated an ischemic process secondary to vasculitis, which accelerated the pathway to colonic perforation. CMV gastrointestinal infection should be considered as a differential diagnosis in patients with colonoscopy findings similar to ischemic colitis and Clostridium difficile infections.
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ISSN:0304-8608
1432-8798
DOI:10.1007/s00705-018-3792-z