Impaired feedforward control of movements in pianists with focal dystonia

• Published in: Frontiers in neurology Vol. 13; p. 983448
• Main Authors: Takiyama, Ken, Mugikura, Shuta, Furuya, Shinichi
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 12.08.2022
• Subjects: data-driven method; feedforward control; focal hand dystonia (FHD); maladaptation; Neurology; skill learning; task-relevant dimension
• ISSN: 1664-2295; 1664-2295
• DOI: 10.3389/fneur.2022.983448

Learning accurate and fast movements typically accompanies the modulation of feedforward control. Nevertheless, it remains unclear how motor skill learning modulates feedforward control, such as through maladaptation of the sensorimotor system by extensive training (e.g., task-specific dystonia). Here, we examined the modulation of feedforward control through motor skill learning while focusing on the motion of piano playing at either a natural tempo or the fastest tempo. The current study compared the kinematics and keypress data among individuals in three groups: healthy and well-trained pianists (i.e., subjects with skill learning), non-musicians (i.e., subjects without skill learning), and patients with focal-hand dystonia (FHD) (i.e., subjects with maladaptation by skill learning). Compared to healthy pianists, patients with FHD showed impairment in some feedforward motion components that are relevant to classifying the two playing tempi. However, while focusing on motion components that are irrelevant to the tempo classification, patients with FHD showed movements comparable to those of healthy pianists. Furthermore, patients with FHD demonstrated significantly slower movement times than healthy pianists. Our results suggest that maladaptation by skill learning affects parts of feedforward control rather than its entirety. Nevertheless, the affected feedforward components are relevant to performing movements as fast as possible, which may underlie the speed dependence of dystonic symptoms.