Review-Field-Effect Transistor Biosensing: Devices and Clinical Applications

Biosensor research has been addressed as an interested field recently. Within different kinds of developed biosensing technologies, field-effect transistor (FET) based biosensors stand out due to their attractive features, such as ultra-sensitivity detection, mass-production capability, and low-cost...

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Bibliographic Details
Published inECS journal of solid state science and technology Vol. 7; no. 7; pp. Q3196 - Q3207
Main Authors Syu, Yu-Cheng, Hsu, Wei-En, Lin, Chih-Ting
Format Journal Article
LanguageEnglish
Published The Electrochemical Society 01.01.2018
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Summary:Biosensor research has been addressed as an interested field recently. Within different kinds of developed biosensing technologies, field-effect transistor (FET) based biosensors stand out due to their attractive features, such as ultra-sensitivity detection, mass-production capability, and low-cost manufacturing. To promote understandings of the FET based biosensing technology, in this review, its sensing mechanism is introduced, as well as major FET-based biosensing devices: ion sensitive field-effect transistor (ISFET), silicon nanowire, organic FET, graphene FET, and compound-semiconductor FET. In addition to FET-based biosensing devices, clinical applications, such as cardiovascular diseases (CVDs), cancers, diabetes, HIV, and DNA sequence, are also reviewed. In the end, several critical challenges of FET-based biosensing technology are discussed to envision next steps in healthcare technologies.
Bibliography:0291807JSS
ISSN:2162-8769
2162-8769
2162-8777
DOI:10.1149/2.0291807jss